Ensembl Anopheles

 

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About the Anopheles genome

VectorBase Ensembl data and displays for Anopheles gambiae are made possible through a joint effort by the Ensembl group and VectorBase, a NIAID Bioinformatics Resource Center. Please access this genome and other resources via the Vectorbase browser.

Assembly

The genome assembly presented here (AgamP3, February 2006) is a revised assembly based on the whole genome shotgun assembly of the PEST strain of Anopheles gambiae produced by the The International Anopheles Genome Project and described in Holt et al (October 2002) with revisions as described in Sharakhova et al (2007). More details can be found at VectorBase.

Annotation

Annotation of the AgamP3 assembly was carried out by VectorBase. The set of gene models presented (genebuild 4, released June 2007) combines manual annotation of chromosome arm 2L, data provided by the research community, and gene prediction using the Ensembl system. Prediction utilised alignments of dipteran and other protein sets to the genome and generation of GeneWise models, alignment and gene prediction based on Anopheles ESTs, and selected ab initio predictions. 'Known' genes are those which could be named using entries from the community gene symbol database or from UniProt. More details can be found at VectorBase.

What's New in Ensembl 46

Anopheles gambiae News

  • Stable ID patches
    Missing creation and deletion events have been added to the stable_id_event table in the mapping_sessions for Anopheles and Takifugu, as these species have changed their stable ID format.
  • Mosquito Xrefs
    More xrefs have been added to the Anopheles database.

General News

  • Functional genomics
    eFG will contribute the second version of the regulatory build with focus on CD4 T-cells comprising more than 20 different epigenetic factors.
  • API changes

    The following changes have been made to the Ensembl API.
    Read more...

  • ncRNA updates
    ncRNAs have been updated for all chordate species, using models from the new version of Infernal.

More news...

New Identifiers

From genebuild 4, VectorBase stable identifiers for genes, transcripts and proteins are used instead of Ensembl-style identifiers. All VB identifiers for Anopheles gambiae begin with the 4 letters AGAP. The same numeric value is used for a gene and all its products. Alternate products of a single gene have suffixes ending A, B, C etc.

Ensembl-style identifiers in the previous genebuild have been mapped where possible to the new identifiers. The web browser page IDHistoryView summarises relationships between old and new identifiers. This page can be reached by clicking the 'ID history' link at the left of each gene view page or from the search results for an unmapped old-style identifier. You can also use HistoryView to enter a list of old-style identifiers and return a list of current equivalents.

Example: Gene CPR34 has the VB identifier AGAP006864, with transcript AGAP006864-RA and protein AGAP006864-PA. The corresponding old identifiers were gene ENSANGG00000020866, transcript ENSANGT00000023320 and protein ENSANGP00000024283.

Links

Statistics

Assembly: AgamP3, Feb 2006
Genebuild: VectorBase, Jun 2007
Database version: 46.3i
Known genes: 1,316
Novel genes: 11,141
RNA genes: 488
Gene exons: 52,595
Gene transcripts: 13,133
SNPs: 1,106,441
Base Pairs*: 278,253,050
Golden Path Length**: 273,093,681
Most common InterPro domains: Top 40 Top 500

* Total number of base pairs = sum of lengths of DNA table

** Reference assembly (Golden path) length = sum of non-redundant top level seq regions


 

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Ensembl release 46 - Aug 2007
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